The other political issue in the spotlight is the resignation of Sen. Sen. Martinez (R-FL) and Sen. Bailey-Hutchinson (R-TX). On one hand these two Senators have been general supporters of immigration reform and so their resignations are unwelcome. Sen. Bailey-Hutchison particularly has been a leader on healthcare visa reform.
On the other hand, since both are Republicans, their influence in Senatorial matters is negligible at this point. Also, since they both are from states with increasing immigration populations, it is expected that any replacements will be unlikely to hinder any CIR legislation. To do so would alienate their constituency.